ssutil is an R package providing a suite of tools for sample size estimation and power simulation in a variety of clinical trial designs. It includes methods for binomial, normal, and negative binomial endpoints, as well as support for equivalence and non-inferiority testing scenarios. It also includes functionality for power and sample size calculation for selecting the best group using the indifferent-zone approach for normal and binomial outcomes.
Features
- Empirical power simulation for:
- Binomial, normal, and negative binomial endpoints
- Equivalence and non-inferiority designs
- Best group selection using the indifferent-zone approach for normal and binomial outcomes
- Sample size utilities for various design types
Installation
# Install from GitHub (requires remotes or devtools)
remotes::install_github("johnaponte/ssutil")